Real semaglutide and tirzepatide. Prescribed by a physician.
Semaglutide and tirzepatide protocols paired with hormone optimization, strength training, and protein-prioritized eating. The medication does the heavy lifting, the system makes it last.
GLP-1 receptor agonists (semaglutide, tirzepatide, and the upcoming retatrutide) are the most effective pharmacologic tools for weight loss in human medicine. At Magnolia Men's Health in Southlake, TX, our protocol pairs the medication with muscle-preservation infrastructure most clinics skip: protein intake targets, a 3-day strength program included at no extra cost, and TRT pairing where appropriate. Compounded semaglutide $199/month, compounded tirzepatide $399/month — both include medication, dose escalation, weekly check-ins, and labs.
GLP-1 receptor agonists work. The data are unambiguous: in placebo-controlled phase III trials, semaglutide produces roughly 15% body-weight reduction and tirzepatide closer to 20% over 12–18 months.12 The 2023 SELECT trial confirmed a 20% reduction in major adverse cardiovascular events in patients with established CV disease.3
The catch is what happens when you stop. Patients who treat the medication as the entire program tend to regain weight when therapy ends. Patients who use the medication as a tool, while they rebuild eating habits and protect their lean mass through resistance training, hold their losses durably. The medication makes the deficit easier; the system makes the result last.
Different mechanisms, different intensities, different price points. We choose what fits your goals, your tolerance, and your budget.
Single-receptor GLP-1 agonist. Longer track record, generally well-tolerated. Average ~14.9% weight reduction at 68 weeks (STEP-1).1 Cardiovascular benefit demonstrated (SELECT).3
Dual receptor, GLP-1 plus GIP. More aggressive: ~20.9% weight reduction at 72 weeks (SURMOUNT-1).2 Higher cost, similar tolerability profile in our experience.
Most online clinics mail you medication and call it done. We don't.
Online clinics ship you a vial and call it done. We sit down monthly to look at body composition, training adherence, protein intake, and side-effect tolerance — then adjust dose to what your body is actually doing.
Lean-mass protection isn't an afterthought. It's the difference between losing weight and losing the right kind of weight.
On-site testosterone test, body composition scan, and a fifteen-minute consultation with the medical director. We order the metabolic baseline panel; this is typically billable to insurance.
Once your labs are back we start at the lowest dose, train your injection technique, and set the resistance-training and nutrition plan. Medication ships from the compounding pharmacy or is picked up at the clinic.
Monthly physician check-ins through dose escalation. Quarterly re-panel and body composition scan. Plan the off-ramp at goal weight so the medication isn't doing all the work.
Most common. Nausea, fatigue, constipation, and reflux during dose escalation. Most resolve in 2–4 weeks at a given dose. We slow titration or hold dose increases when symptoms are limiting.
Less common. Gallbladder pathology (cholecystitis, biliary colic) particularly with rapid weight loss. Pancreatitis (rare). Vomiting severe enough to require dose hold.
Boxed warning. Both semaglutide and tirzepatide carry an FDA boxed warning regarding medullary thyroid C-cell tumors based on rodent data. Humans do not appear to share this risk in available human studies, but we screen for personal or family history of MTC and MEN2 syndrome before starting.
We bill insurance for the office visit and the metabolic panel. Brand-name Wegovy or Zepbound is occasionally covered for documented obesity diagnoses; we'll verify before starting if you'd prefer the brand path.
I lost 38 pounds in seven months. The difference between Magnolia and the online clinic I tried first is that someone actually built a plan with me. I added back two days of weight training, my testosterone got optimized at the same time, and I held the loss when I tapered off.
Dr. Abdullah is a board-certified internal medicine physician based in Southlake, TX, and an IFM-certified functional medicine practitioner. He focuses on men's hormone health — testosterone optimization, GLP-1 weight loss, sexual health, peptides, and longevity — and personally reviews and adjusts every protocol that leaves the clinic.
Fifteen-minute free first visit at our Southlake clinic. Serving Westlake, Trophy Club, Colleyville, Keller, Grapevine, Roanoke, and the broader Dallas–Fort Worth metro.
or call (817) 749-6946